For treestand hunting I will try to stand when it is what I consider prime time, mornings or evenings. Of course when I get tired of standing I will rest a bit. When it comes to the shot I always try to stand up, that way I can bend at the waist to make the shot. Only once was I sitting when I took a shot, my first deer, and the bottom of my bow hit the stand causing the arrow to hit the deer back. Found him though.

In a ground blind I usually am sitting unless getting to my knees is a better shot.